mAbPredictAI
mAbPredictAI is the AI-enabled module of the Rational Antibody Discovery platform that leverages data-rich, systems biology approaches to identify critical functional regions of a target protein. mAbPredict determines the disease-associated epitopes that mAbHits AbvantageTM will engineer an immune response towards.
AI-Enabled Identification of Functional Epitopes
To identify potentially valuable epitopes, mAbPredictAI will deploy all structural and functional knowledge of the target:
Sequence
Sequence
Curated databases contain sequence information, including homologs and variants
Structure
Structure
Determine structure experimentally e.g. cryo-electron microscopy or computationally e.g. homology modeling
Function
Function
Mutagenesis can identify critical epitopes which impact the function of the target
